Description
PNC-27 is a synthetic peptide containing an HDM-2 binding domain derived from the p53 tumor suppressor protein, linked to a cell-penetrating peptide. It is studied in preclinical research for its selective interaction with HDM-2 protein expressed on the surface of transformed cells.
Research indicates that PNC-27 binds to HDM-2 on the plasma membrane of transformed cells, leading to membrane disruption through a necrotic mechanism. It serves as a research tool for investigating p53-HDM-2 interactions and selective targeting mechanisms in oncology research.
Specifications:
CAS Number: N/A
Molecular Formula: Modified Peptide (p53-HDM2 Fragment)
Molecular Weight: ~3200 g/mol
Purity: ≥99% (HPLC Verified)
Physical Form: Lyophilized Powder
Storage: Store at -20°C, protected from light
For research use only. Not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease.
Reviews
There are no reviews yet.