Description
ACE-031 is a soluble form of the activin receptor type IIB (ActRIIB) fused to the Fc domain of human IgG1. It is studied in preclinical research as a ligand trap for myostatin, activin, and other TGF-beta superfamily members.
Research indicates that ACE-031 sequesters circulating myostatin and activin ligands, preventing their interaction with membrane-bound ActRIIB receptors. This blockade is studied for its effects on Smad2/3 signaling, muscle mass regulation, and metabolic pathways in laboratory models.
Specifications:
CAS Number: 1052405-50-5
Molecular Formula: Fusion Protein (ActRIIB-Fc)
Molecular Weight: ~90,000 g/mol
Purity: ≥99% (HPLC Verified)
Physical Form: Lyophilized Powder
Storage: Store at -20°C, protected from light
For research use only. Not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease.





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