Description
ARA-290 is an 11-amino acid peptide derived from the helix B surface of erythropoietin (EPO). It is studied in preclinical research for its tissue-protective effects mediated through the innate repair receptor (IRR), a heterodimer of EPO receptor and beta common receptor, without erythropoietic activity.
Research indicates that ARA-290 activates IRR-mediated signaling cascades including JAK2/STAT5 and NF-kappaB pathways, promoting cytoprotection and anti-inflammatory responses. It serves as a tool compound for studying non-hematopoietic EPO receptor signaling.
Specifications:
CAS Number: N/A
Molecular Formula: C51H84N18O17
Molecular Weight: 1201.33 g/mol
Purity: ≥99% (HPLC Verified)
Physical Form: Lyophilized Powder
Storage: Store at -20°C, protected from light
For research use only. Not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease.
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