Description
FOXO4-DRI is a D-retro-inverso peptide designed to disrupt the interaction between FOXO4 and p53 transcription factors in senescent cells. It is studied in preclinical research for its role in cellular senescence mechanisms and aging biology.
Research indicates that FOXO4 sequesters p53 in the nucleus of senescent cells, preventing apoptosis. The DRI peptide interferes with this interaction, releasing p53 to execute apoptotic programs selectively in senescent cells. It serves as a tool for investigating senescence-associated signaling.
Specifications:
CAS Number: N/A
Molecular Formula: Modified Peptide
Molecular Weight: ~5000 g/mol
Purity: ≥99% (HPLC Verified)
Physical Form: Lyophilized Powder
Storage: Store at -20°C, protected from light
For research use only. Not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease.





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